Vitamin B6, also known as pyridoxine, is one of eight B vitamins that your body needs to stay healthy.

This nutrient is an essential part of nearly 200 chemical reactions in your body, and it’s necessary for processes like brain development and transporting oxygen through your bloodstream. Vitamin B6 also helps you maintain a healthy nervous and immune system.

Food sources of vitamin B-6 include poultry, fish, potatoes, chickpeas, bananas and fortified cereals. Vitamin B-6 can also be taken as a supplement.

People who have kidney disease or conditions that prevent the small intestine from absorbing nutrients from foods (malabsorption syndromes) are more likely to be vitamin B-6 deficient. Certain autoimmune disorders, some epilepsy medications and alcohol dependence also can lead to vitamin B-6 deficiency. This can cause a condition in which you don’t have enough healthy red blood cells to carry adequate oxygen to your body’s tissues (anemia), confusion, depression and a weakened immune system.

A vitamin B-6 deficiency is usually coupled with deficiency in other B vitamins, such as folic acid (vitamin B-9) and vitamin B-12.

 Some of Benefits of Vitamin B6:

  • Low levels of vitamin B6 in older adults have been linked to depression, but research has not shown that B6 is an effective treatment for mood disorders.
  • Vitamin B6 may prevent a decline in brain function by decreasing homocysteine levels that have been associated with Alzheimer’s disease and memory impairments. However, studies have not proven the effectiveness of B6 in improving brain health.
  • Not getting enough vitamin B6 can lead to low hemoglobin and anemia, so supplementing with this vitamin may prevent or treat these issues.
  • Some research has indicated that high doses of vitamin B6 may be effective at decreasing anxiety and other mood issues associated with PMS due to its role in creating neurotransmitters.
  • Vitamin B6 supplements in doses of 30–75 mg a day have been used as an effective treatment for nausea and vomiting during pregnancy.
  • Vitamin B6 may help reduce high homocysteine levels that lead to narrowing of arteries. This may minimize heart disease risk.
  • Vitamin B6 supplements may reduce your risk of age-related macular degeneration (AMD). Additionally, adequate blood levels of B6 may prevent issues that affect the retina. However, more research is needed.
  • Inflammation associated with rheumatoid arthritis may lower blood levels of vitamin B6. Supplementing with high doses of B6 may help correct deficiencies and reduce inflammation, but more research is needed to confirm these effects.
  • Vitamin B-6 (pyridoxine) is important for normal brain development and for keeping the nervous system and immune system healthy.

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